An Open Letter To Dutch Politician Klaas Dijkhoff Over Vaccination Causing Autism
According to Dutch politician and VVD Chairman Klaas Dijkhoff, vaccines cannot hurt or is harmful. Meanwhile, vaccinated neonates' boys had threefold greater odds for autism.
Dutch politician and VVD chairman Klaas Dijkhoff think of a vaccination obligation if more and more parents in the Netherlands refuse to vaccinate their child against deadly diseases.
Dijkhoff is seriously concerned about the growing number of parents who, on the basis of non-scientific arguments, decide to abstain from voluntary prevention against serious diseases such as measles. And he is adviced by persons like Peter Rost and virologists like Ab Osterhaus.
VVD Chairman Klaas Dijkhoff
According to Dijkhoff, a whole new group of highly educated vaccine rejecters has emerged. These well educated 'anti-vaxxers', indicates that education level does not say everything. But Dijkhoff apparently isn’t aware many of these highly educated persons are of a scientific level?
They refuse not on religious grounds, but on the basis of sources that claim that vaccination increases the risk of autism (a claim made by a now proven fraudster), that there are scary substances (there are substances in the vaccine that sound scary, because in high doses are harmful, but that is true, but in too high doses, water is also deadly, so it's about how much of that substance is in.
That determines whether something is helpful, cannot hurt or is harmful. are not harmful doses) and other pseudo-interesting bullshit.
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But Klaas? This so-called pseudo-interesting bullshit you mention is also published by well-known scientists in well-known scientific journals? And indeed they are very educated as well. Did not you cut the legs under your own chair and below those of your advisers?
Boys vaccinated as neonates had threefold greater odds for autism
For instance Klaas, universal hepatitis B vaccination was recommended for U.S. newborns in 1991; however, safety findings are mixed. The association between hepatitis B vaccination of male neonates and parental report of autism diagnosis was determined. This cross-sectional study used weighted probability samples obtained from National Health Interview Survey 1997-2002 data sets.
Vaccination status was determined from the vaccination record. Logistic regression was used to estimate the odds for autism diagnosis associated with neonatal hepatitis B vaccination among boys age 3-17 years, born before 1999, adjusted for race, maternal education, and two-parent household.
Boys vaccinated as neonates had threefold greater odds for autism diagnosis compared to boys never vaccinated or vaccinated after the first month of life. Non-Hispanic white boys were 64% less likely to have autism diagnosis relative to nonwhite boys.
Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period. Nonwhite boys bore a greater risk.
Oh, Klaas Moreover, to address a possible environmental contribution to autism, a study is carried out about a retrospective study on urinary porphyrin levels, a biomarker of environmental toxicity, in 269 children with neurodevelopmental and related disorders referred to a Paris clinic (2002-2004), including 106 with autistic disorder.
Urinary porphyrin levels determined by high-performance liquid chromatography were compared between diagnostic groups including internal and external control groups.
Coproporphyrin levels were elevated in children with autistic disorder relative to control groups. Elevation was maintained on normalization for age or to a control heme pathway metabolite (uroporphyrin) in the same samples.
The elevation was significant (P < 0.001). Porphyrin levels were unchanged in Asperger's disorder, distinguishing it from autistic disorder. The atypical molecule precoproporphyrin, a specific indicator of heavy metal toxicity, was also elevated in autistic disorder (P < 0.001) but not significantly in Asperger's.
A subgroup with autistic disorder was treated with oral dimercaptosuccinic acid (DMSA) with a view to heavy metal removal. Following DMSA there was a significant (P = 0.002) drop in urinary porphyrin excretion. These data implicate environmental toxicity in childhood autistic disorder.
Yes Klaas, autism, is a member of the pervasive developmental disorders (PDDs), and has been increasing dramatically since its description by Leo Kanner in 1943. First estimated to occur in 4 to 5 per 10,000 children, the incidence of autism is now 1 per 110 in the United States, and 1 per 64 in the United Kingdom, with similar incidences throughout the world.
Klaas are you there?
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Autism could result from more than one cause, with different manifestations in different individuals that share common symptoms.
Documented causes of autism include genetic mutations and/or deletions, viral infections, and encephalitis following vaccination. Therefore, autism is the result of genetic defects and/or inflammation of the brain.
The inflammation could be caused by a defective placenta, immature blood-brain barrier, the immune response of the mother to infection while pregnant, a premature birth, encephalitis in the child after birth, or a toxic environment.
Furthermore, Klaas Dijkhoff, recent animal and human studies have underscored the strong influence of genetic, epigenetic, and physiologic factors in defining susceptibility of the immune system to methylmercury (MeHg) and ethylmercury (EtHg) Immune dysregulation triggered by organic mercury can include suppression, stimulation, loss of tolerance, and generation of auto-antibodies.
Therefore, the pattern of immunotoxicity induced by organic mercury is likely to depend not only on the chemical form, timing, and dose to which an individual is exposed but also on susceptibility factors that are poorly understood at present.
Thus, significant attention is currently focused on identifying which types of immune cells and biomolecules are critical targets of low-level organic mercury and their functional consequences on overall immune status.
Sodium ethylmercurithiosalicylate (thimerosal; THI) is an EtHg-containing compound used to preserve cosmetics, blood products, and vaccines and is also used experimentally to induce calcium (Ca2+) release from microsomal [endoplasmic reticulum/sarcoplasmic reticulum (ER/SR)] stores in intact cells.
Finally, Dutch politician and VVD chairman Klaas Dijkhoff, a recent report shows a correlation of the historical use of thimerosal in therapeutic immunizations with the subsequent development of autism; however, this association remains controversial.
Autism occurs approximately four times more frequently in males compared to females; thus, studies of thimerosal toxicity should take into consideration gender-selective effects. The present study was originally undertaken to determine the maximum tolerated dose (MTD) of thimerosal in male and female CD1 mice.
However, during the limited MTD studies, it became apparent that thimerosal has a differential MTD that depends on whether the mouse is male or female. At doses of 38.4-76.8mg/kg using 10% DMSO as a diluent, seven of seven male mice compared to zero of seven female mice tested succumbed to thimerosal.
Although the thimerosal levels used were very high, as we were originally only trying to determine MTD, it was completely unexpected to observe a difference of the MTD between male and female mice.
Thus, our studies, although not directly addressing the controversy surrounding thimerosal and autism, and still preliminary due to small numbers of mice examined, provide, nevertheless, the first report of gender-selective toxicity of thimerosal and indicate that any future studies of thimerosal toxicity should take into consideration gender-specific differences.
Dear Klaas Dijkhoff, do you indicate that education level does not say everything about the aforementioned scientists and hundreds more? If so, then you will reap what you've sown.
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