Kumasi Asante Kotoko have an opportunity to avenge defeat to old foes Accra Hearts of Oak when the two sides clash on Sunday at Cape Coast in the Onetouch Top 4 competition, while Kpando Heart of Lions will attempt to devour Berekum Arsenal at the Sunyani Coronation Park.
In the run-up to their Premiership success last season, the Phobians achieved a decisive back-to-back victories over the Fabulous lads on Christmas Eve and a week later.
They were painful defeats that sped up the exit of Kotoko's Turkish coach Telat Uzum.
Now, five months later the stage is all set for the Oseikrom lads to take their pound of flesh and breath life back into their Top 4 ambitions after sharing points with Arsenal after a scoreless match at Sunyani last Sunday.
After losing 0-1 to Lions last Sunday, another defeat could be too costly for the Phobians and is likely to scuttle their title hopes.
In-form Lions are on the prowl and are clear and present danger for the stubborn Arsenal side. The two clubs recorded a win each in the league, with Arsenal winning 3-1 at Berekum while Lions earned a 2-1 victory at Kpandu, thus making Sunday's tie even trickier.