Algerian striker Rafik Djebbour returned to his scoring form to give Panionios the lead after 4 minutes in a 1-1 draw with Iraklis Saloniki.
The Desert Fox has now scored four goals so far this season, as has DR Congo's Lomana LuaLua.
The striker scored his fourth for Olympiakos in the 30th minute in a 3-1 win over Atromitos to leave his side third in the table.
Ismael Bangoura scored from the penalty spot to equalise for Dynamo Kiev in the 18th minute as they came from behind to triumph 5-2 over Chernomorets Odessa.
The Guinean striker is the third highest top scorer with eight goals and Kiev are third in the table after 18 games.
Senegal's Mbaye Leye scored twice on his 25th birthday to help Zulte Waregem defeat Charleroi 3-2.
The striker put his side ahead after just three minutes before scoring the second in the 58th.
Congolese striker Patiyo Tambwe was on target for Lokeren, giving them the lead in the 1-1 draw with Cercles Bruges.
There were no fewer than four African scorers in the seven-goal thriller between FC Malines and Roulers.
It was the Cameroonian Aloys Nong, who opened the flood gates in the 18th minute with the first of his two goals for Malines.
His Ghanaian team mate Nana Asare made it 4-2 midway in the second half.
Sierra Leonean striker Paul Kpaka and Malian Mahamadou Dissa were the African scorers for Roulers.
DR Congo's Zola Matumona secured a point for FC Brussels thanks to his 85th minute equaliser to make the final score 1-1 with Mouscron.
Ivory Coast's Boubacar Sanogo put Werder Bremen ahead against Hamburg, before Rafael van der Vaart equalised on 61 minutes with a superb 25-metre lob.
Bremen went on to win 2-1 to continue a 10 league-game unbeaten run and to rise to the top of the division.
At the foot of the table a 90th minute goal meant heart break for bottom club Levante as they went down 2-1 to Getafe.
Levante took the lead after 15 minutes when Ghana's Riga Mustapha followed up and slotted home a rebound from his own poorly taken penalty.
However, Getafe equalised just after the hour and then sealed the victory in the dying moments of the match.
Nigeria striker Isaac Promise scored the winning goal for his side Genclerbirligi early in the first half in a 2-1 defeat of Trabzonspor.
It was only the third win in 14 games for Genclerbirligi who are still in the relegation zone, situated third from bottom.
Elsewhere Malian defender Mamoutou Coulibaly was sent-off 10 minutes before the end of the game as his side Kasimpasa were beaten 2-0 at home by Bursaspor.
Ivorian striker Gervais Yao Kouassi was on the score sheet for the first time this season, scoring the winner for Le Mans in their 2-1 triumph over Nancy.
Fellow Ivorian Aruna Dindane gave Lens the lead in the 2-0 victory over Sochaux to claim his fourth of the season.
Algeria midfielder Rafik Saifi scored his seventh after his 75th minute equaliser for Lorient in the 1-1 draw with St Etienne.
Senegal striker Mamadou Niang earned struggling Marseille one point after he drew level for them in the 1-1 draw with Lille.
Ghana defender John Mensah was shown the red card in the second-half as his side Rennes were beaten 3-0 by Valenciennes.
Ghana's Francis Dickoh got the fifth goal as his side Utrecht hammered Sparta Rotterdam 7-1.
Moroccan Said Boutahar also played a part in Willem II's 6-0 massacre of another Rotterdam side Excelsior.
Boutahar scored his side's third.
Ghanaian striker Matthew Amoah scored the second goal for NAC Breda in their spectacular 3-1 victory in Amsterdam over Ajax.
Togo striker Emmanuel Adebayor's eighth league goal of the season helped inspire Premier League leaders Arsenal to a memorable victory at Aston Villa.
Adebayor produced a dashing, all-round display for Arsenal who maintained their unbeaten league record with a 2-1 victory at Villa Park.
He scored with a thumping header from Bacary Sagna's cross after 36 minutes to put Arsenal ahead.
Elsewhere, Obafemi Martins gave Newcastle United the lead but the Nigerian striker could not help his side eventually being beaten 3-1 by Blackburn Rovers.
Martins scored with a header from Geremi's freekick.