Seven are feared dead while others are in a critical condition after a gory accident.
The bloody accident was said to have happened at a portion in-between Ejisu and Konongo on the Kumasi-Accra highway on Friday afternoon.
The bodies of the dead have since been deposited at the morgue of a medical facility at Juaben for autopsy.
This was after a bus from Accra to Kumasi collided head-on with another bus, which was from the opposite direction to Accra.
Eyewitnesses accused the driver of the bus from Kumasi of committing a blunder that led to the deadly crash.
The offending driver, upon reaching Kubease, tried to do wrong overtaking and in the process collided head-on with the oncoming bus.
According to eyewitnesses, the impact of the collision was so heavy that seven people died instantly while some of the passengers suffered serious injuries.