Residents of Atonsu Bokro Abeasi, a Kumasi suburb, watched in agony when a 28-year-old man, Alfred Anokye Manu, was burnt to death early Wednesday.
The rampaging fire trapped the victim in his room, burning him to death.
A number of household items, including a television set, radio, clothes and cooking utensils, were also destroyed in the outbreak.
Four rooms in the five-bedroom house were destroyed by the fire.
It took firemen about three hours to bring the fire under control to prevent it from spreading to other houses.
The Ashanti Regional Fire Officer, Mr Philip Arhin Mensah, said the cause of the fire was yet to be established.
An eyewitness told the Daily Graphic that the fire started at dawn, saying that when neighbours realised its intensity, they alerted firemen and also rushed to the scene to help bring it under control.
He said firemen who arrived at the scene had to battle the fire for more than three hours before they were able to bring it under control and retrieve the charred body of the victim.
Manu's body has been deposited at the Komfo Anokye Teaching Hospital (KATH) mortuary for autopsy pending further investigations into the incident.


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