Mighty Jets clash with Maamobi Midtjiland on Sunday on the opening weekend of the division One league in Zone 3A at Amasaman.
The match has been dedicated to the late founder of Midtjiland Alhaji Bimbo who died last August.
Abedi Pele's Nania FC return from their one-year ban and face a tough tie against last season's Premier League campaigners Real Sportive at the Legon Park.
On Saturday, Fairpoint will play Great Mariners also in Zone 3A.
In zone 1B, rivals Aduana Stars face BA United, Bofoakwa host Moonlight FC.
Feyenoord begin another campaign to the top flight league against Metro FC away in Zone 2B on Saturday and Dwarfs play Starke FC.
Corners host Mine Stars in Zone 2A and West Ham engage Norchip in Zone 2B.
The Zone 3 fixtures will begin in a two-weeks time.
For more Ghana football news visit www.ghanasoccernet.com