Scientists and amateur stargazers alike are looking forward to observing the sunlit plume of rubble and debris that is expected after the Falcon 9 upper stage strikes the lunar surface at approximately 2:35am Eastern (0635 GMT.)
"It might be possible for folks with a telescope to observe the plume of ejecta created by the impact," said Benjamin Fernando of Los Alamos National Laboratory in New Mexico, the lead author on a recent paper on the anticipated impact.
"It is unclear how bright it will be, which is one of the reasons why we are looking to study this event," the researcher told AFP.
Assuming all of the propellant is spent, authors of the paper estimate the spacecraft weighs approximately 8,800 pounds (4,000 kilograms).
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It is expected to slam into the Moon's northern hemisphere near the Einstein Crater, at some 5,400 miles per hour (8,690 kilometres per hour).
"There is no danger to Earth," said NASA spokesperson Jimi Russell in a statement.
"NASA will continue to track the booster for training purposes, as well as later observe the impact site for scientific purposes."
The Falcon 9 rocket took off last January, carrying two lunar landers. The booster returned to Earth, but the upper stage stayed in space to push the landers onward.
Generally, for such "high-energy missions", SpaceX performs a maneuver to make sure the second stage "is safe per the appropriate rules and regulations", said Julianna Scheiman, director of NASA Science and Dragon Programs at SpaceX, at a Monday news conference.
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"We did that," she continued, but "what has happened is essentially a mixture of solar activity and gravity forces have put it on a path towards the Moon".
Like many scientists, Scheiman added that "I also am very excited to see the observation."
The paper's authors encouraged both professional and amateur astronomers to attempt viewing or recording the collision.
"This event provides an opportunity to test a pipeline for localising impacts on the lunar surface for future seismic experiments, investigating the dust and plume dynamics from impact events on the Moon, and considering hazards from artificial space debris impacts," wrote the research team.
NASA hopes to soon establish a sustained human presence on the Moon, making it critical to better understand space debris in lunar orbit.
The Moon routinely weathers impact from space debris including meteoroids. Artificial collisions are less common.
In the 1970s, the US space agency carried out deliberate crashes during its Apollo program to collect seismic data.
(FRANCE 24 with AFP)



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