Today, at four, centres in and around Accra and Kumasi, eight teams begin the search for two places in next season's premiership.
Zone 1's Chelsea, Upper Stars, B.A. United and Soccer Warriors will confine hostilities to the Prempeh College and Baba Yara Stadium in Kumasi, while Eleven Wise, Norchip, Samartex and Westham will battle it out at the Carl Reindorf Park at Dansoman in Accra and the Tema Stadium for the one week the Division One Middle League will last.
Chelsea and Upper Stars will do battle at the Prempeh College, while B.A. United take on Chelsea at the Baba Yara Stadium in the opening games of Zone 1.
For B.A. United, the chance to return to the elite league again after five years in Ghana football's wilderness has been the inspiration for the seriousness that has characterised their preparation for the Middle League so far.
In Kumasi where thousands of their fans are expected to arrive to watch each of their three games, B.A. United appear to be in comfort zone where Chelsea will have to reach deep into their reserves to contain their opponents.
Similar tough games are expected at Dansoman where Wise, another side seeking a return to premiership football, play Norchip, and at Tema where Samartex and Westham will attempt to undo each other.
Meanwhile, the Division One League (DOL) Board of the Ghana Football Association will meet St Mirren, Fair Point, Royal Knights and Power FC to discuss the start of the competition in Zone 3.
The meeting, according to Kwame Ntow-Fiako, chairman of the DOL Board, has been necessitated by the verbal notification from King Solomon that they would no longer pursue their appeal against Soccer Learners after the club was stripped of their place in the Middle League.