Struggling AshantiGold inflicted Asante Kotoko's first defeat of the season on Sunday after beating the Porcupine Warriors 1-0.
A well-worked second-half strike by substitute Alex Asamoah was enough to give the visitors the win at the Golden City Park.
Asamoah went through the middle to score with his first touch of the game after being put through with a defence splitting pass to stun the home fans.
The goal was the first conceded by Kotoko after six games of the season so far.
Despite the loss, the Porcupine Warriors still stay top of the standings but have seen their three point lead cut to two.
Hearts' indifferent start to the season continued in spite of the presence of joint new CEOs Harry Zakkour and Thomas Okine as they fell 1-0 to Kessben at the Anane Boateng Stadium
The home team secured a lone goal victory thanks to a second half strike by James Boadu.
The striker was unlucky as his second goal scoring attempt against a disheartened Phobian side was ruled offside.
Kessben FC are now third on the standings with just two points separating them from the league leaders.
King Faisal were strong for Berekum Arsenals at the Len Clay Stadium with a comfortable 2-0 win over the Gunners.
Goals from Ibrahim Basich in the first half and a second half strike from Edmund Owusu-Peprah sealed victory for Faisal.
The Swedru Park also recorded victory as home side, Gamba All Blacks posted a lone goal victory over Tema Youth.
Osman Sakora handed the Black Magicians victory with a second half strike.
All two matches in the capital, Accra, failed to produce any goals.
Liberty Professionals and Heart of Lions shared the spoils at the Carl Reindorf Park in their goalless drawn game while Accra Great Olympics and Zaytuna United also drew goalless at the El-Wak Stadium, a result which leaves the Wonder Boys at the bottom of the table with two points from a maximum of 18.
No ball was kicked at the Gyandu Park as the game between Sekondi Hasaacas and Real Tamale United failed to take place due to a clash of jersey colours.
A new set of jersey brought in by the away side, Real Tamale United arrived late after the match referee had called off the game.
Earlier on Saturday, Real Sportive beat Wa All Stars 2-1 at the El-Wak Stadium.
The Blues drew first blood in the 15th minute through Raphael Okyere to put Wa All Stars in the lead.
However, in the second half, Joel Adjei equalised from a spot kick in the 77th minute before substitute, Richard Yeboah, scored the match winner two minutes later.